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Metrics details. Hemorrhagic fever with renal syndrome HFRS is an emerging zoonotic infectious disease caused by hantaviruses which circulate worldwide. So far, it was still considered as one of serious public health problems in China.
The present study aimed to reveal the stabilities and variations of hantavirus infection in Hebei province located in North China through a long-term retrospective observation.
The epidemiological data of HFRS cases from all 11 cities of Hebei province since through were collected and descriptively analyzed.
The rodent densities, species compositions and virus-carrying rates of different regions were collected from six separated rodent surveillance points which set up since The molecular diversity and phylogenetic relationship of hantaviruses circulating among rodents were analyzed based on partial viral glycoprotein gene.
HFRS cases have been reported every year in Hebei province, since the first local case was identified in The epidemic history can be artificially divided into three phases and a total of 55, HFRS cases with deaths were reported during — The gender and occupational factors of susceptible population were invarible throughout, however age of that was gradually aging. The annual outbreak peak always present in spring, while the main epidemic region had gradully altered from south to northeast.